Circadian rhythm disruptions and neurodegeneration through Parkinson disease and cognitive disruptions

Circadian rhythm disorders (CRD) result from modern lifestyles characterized by long exposure time to blue light, shift-work, chronic stress and night-time social activities. The disruption of circadian rhythms represents an individual risk factor in the development various diseases, including neurodegenerative ones. Simultaneously, demographic ageing is associated with rising incidence diseases (ND), cognitive decline becoming a societal problem. Thus, this literature review’s purpose outline interconnexion between CRD – ND disruptions pathophysiological angle based on example Parkinson disease. final objective study depict what are prophylactic measures against brain reserve’s caused order enhance life quality lowering DALY index.